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BARNETT
INSTITUTE RESEARCH PUBLICATIONS
(2003 - present)
Contents:
Prof. Barry L. Karger
Prof. William S. Hancock
Prof. Graham Jones
Prof. Roger Giese
Prof. Bill Giessen
Prof. Paul Vouros
Prof. John Engen
Prof. Zhaohui Sunny Zhou
(click
here for current Pubmed
search "Barnett Institute")
Professor Barry L. Karger
Zang T, Dai S, Chen D, Lee BW, Liu S, Karger BL, Zhou ZS. Chemical
methods for the detection of protein N-homocysteinylation via selective
reactions with aldehydes. Anal Chem. 2009 Nov 1;81(21):9065-71.(pubmed)
Thakur D, Rejtar T, Karger BL, Washburn NJ, Bosques CJ, Gunay NS, Shriver
Z, Venkataraman G. Profiling the Glycoforms of the Intact
alpha Subunit of Recombinant Human Chorionic Gonadotropin by High-Resolution
Capillary Electrophoresis-Mass Spectrometry. Anal Chem. 2009
Nov 1;81(21):8900-7. (pubmed)
Jia Y, Wu SL, Isenberg JS, Dai S, Sipes JM, Field L, Zeng B, Bandle
RW, Ridnour LA, Wink DA, Ramchandran R, Karger BL, Roberts DD. Thiolutin
inhibits endothelial cell adhesion by perturbing Hsp27 interactions
with components of the actin and intermediate filament cytoskeleton.
Cell Stress Chaperones.2009 1355-8145 (link)
Monzo A, Rejtar T, Guttman A. Optimization of poly(GMA-co-EDMA)
Monolithic Support for Trypsin Nanoreactor Fabrication.
J Chromatogr Sci. Jul 2009; 47(6):467-72. (pubmed)
Karger BL, Guttman A. DNA sequencing by CE.
Electrophoresis, Jun 2009; 30 Suppl 1:S196-202.(pubmed)
Lazarev AV, Rejtar T, Dai S, Karger BL. Centrifugal methods
and devices for rapid in-gel digestion of proteins. Electrophoresis.
Mar 2009; 30(6):966-73. (pubmed)
Jiang H, Wu SL, Karger BL, Hancock WS. Mass spectrometric
analysis of innovator, counterfeit, and follow-on recombinant human
growth hormone. Biotechnol Prog. Jan-Feb 2009; 25(1):207-18.
(pubmed)
Dai S, Jia Y, Wu SL, Isenberg JS, Ridnour LA, Bandle RW, Wink DA,
Roberts DD, Karger BL. "Comprehensive Characterization
of Heat Shock Protein 27 Phosphorylation in Human Endothelial Cells
Stimulated by the Microbial Dithiole Thiolutin."
J Proteome Res. 2008 Aug 23. [Epub ahead of print]
pubmed
Baumgartner C, Rejtar T, Kullolli M, Akella LM, Karger BL. "SeMoP:
A New Computational Strategy for the Unrestricted Search for Modified
Peptides Using LC-MS/MS Data." J Proteome Res.
7(9):4199-4208. (2008) pubmed
Alfaro JF, Gillies LA, Sun HG, Dai S, Zang T, Klaene JJ, Kim BJ,
Lowenson JD, Clarke SG, Karger BL, Zhou ZS. "Chemo-enzymatic
detection of protein isoaspartate using protein isoaspartate methyltransferase
and hydrazine trapping." Anal Chem. 80(10):3882-9
(2008) pubmed
Luo Q, Gu Y, Wu SL, Rejtar T, Karger BL. "Two-dimensional
strong cation exchange/porous layer open tubular/mass spectrometry
for ultratrace proteomic analysis using a 10 microm id poly(styrene-
divinylbenzene) porous layer open tubular column with an on-line
triphasic trapping column." Electrophoresis.
29(8):1604-11. (2008) pubmed
Csanky, E., Olivova,
P., Rajnavolgyi, E., Hempel, W., Tardieu, N., Katalin, E.T., Jullien,
A., Malderez-Bloes, C., Kuras, M., Duval, M.X., Nagy, L., Scholtz,
B., Hancock, W.S., Karger, B.L., Guttman, A., Takacs, L., "Monoclonal
Antibody Proteomics: Discovery and Prevalidation of Chronic Obstructive
Pulmonary Disease Biomarkers in a Single Step", Electrophoresis,
28, #23, 4401-4406, (2007). pubmed
Gu, Y., Wu, S-L.,
Meyer, J.L., Hancock, W.S., Burg, L.J., Linder, J, Hanlon, D.W., and
Karger B.L. "Proteomic analysis of high-grade dysplastic
cervical cells obtained from ThinPrep slides using laser capture microdissection
and mass spectrometry." J. Proteome Res. 6(11):4256-68,
(2007). pubmed
Wu, S-L.,
Hühmer, A.F., Hao, Z., and Karger, B.L. "On-line LC-MS approach
combining collision-induced dissociation (CID), electron-transfer
dissociation (ETD), and CID of an isolated charge-reduced species
for the trace-level characterization of proteins with post-translational
modifications." J. Proteome Res. 6(11):4230-44,
(2007). pubmed
Zvonok,
N., Yaddanapudi, S., Williams, J., Dai, S., Dong, K., Rejtar, T.,
Karger, B.L. and Makriyannis, A., " Comprehensive Proteomic Mass
Spectrometric Chracterization of Human Cannabinoid CB2 Receptor",
J. Proteome Research, 2068-2079, (2007).pubmed
Zhang,
J., Wu, S., Kim, J. and Karger, B.L., "Ultratrace liquid chromatography/mass
spectrometry analysis of large peptides with post-translational modifications
using narrow-bore poly(styrene- divinylbenzene) monolithic columns
and extended range proteomic analysis", J. Chromatogr A.,
1154, 295-307, (2007).pubmed
Luo, Q., Yue,
G., Valaskovic, G., Gu, Y., Wu., S-L. and Karger, B.L. "On-Line
1D and 2D PLOT/LC-ESI-MS Using 10 µm i.d. Poly(styrene-divinylbenzene)
Porous Layer Open Tubular (PLOT) columns for Ultrasensitive Proteomic
Analysis", Anal. Chem., ASAP Article; DOI:
10.1021/ac070583w (2007).
Ren, J.M., Rejtar, T., Li, L. and Karger, B.L. "Automated N-Glycan
Structure Annotation of Glycopeptides Using a Linearized Structure
database (GlyDB)", J. of Proteome Research, 6, 3162-3173,
(2007).
Andreev, V., Li,
L., Cao, L., Gu, Y., Rejtar, T., Wu, S-L. And Karger, B.L. "
A New Algorithm Using Cross-Assignment for Label-Free Quantitation
with LC/LTQ-FT MS", J. of Proteome Res., 6, 2186-2194
(2007).
Li, L., Li, Q.,
Rohlin, L., Kim, U., Salmon, K., Rejtar, T., Gunsalus, R.P., Karger,
B.L. and Ferry, J.G. "Quantitative proteomic and microarray analysis
of the archaeon Methanosarcina acetivorans grown with acetate versus
methanol", J. of Proteome Res, 6, 759-771, (2007).
Yue, G. Luo, Q., Zhang, J., Wu, S. And Karger B.L.,"Ultratrace
LC/MS Proteomic Analysis Using 10 µm i.d. Porous Layer Open
Tubular (PLOT) Poly(styrene-divinylbenzene) Capillary Columns",
Anal. Chem, 79 (3), 938-946, (2007).
Lessner, D., Li,
L., Li, Q., Rejtar, T., Andreev, A., Reichlen, M., Hill, K., Moran,
J., Karger, B.L. and Ferry, J. G. "An Unconventional Pathway
for Reduction of CO2 to Methane in CO-grown Methanosarcina Acetivorans
Revealed by Proteomics" PNAS (103) 17921, (2006).
Correia, F., D'Onofrio,
A., Rejtar,T., Li, L., Karger, B.L., Makarova, K., Koonin, E.V., and
Lewis, K., "Kinase Activity of Overexpressed HipA is Required
for Growth Arrest and Multidrug Tolerance in Escherichia coli",
J. of Bacteriology, vol. 188 (24) 8360-8367, (2006).
Wu, S.L., Kim,
J., Bandle, R., Liotta, L., Petricoin, E. And Karger, B.L., "Dynamic
profiling of the post-translational modifications and interaction
partners of epidermal growth factor receptor signaling after stimulation
by EGF using extended range proteomic analysis (ERPA)", Mol.
Cell,. 5, 1610-1627, (2006).
Andreev, V.,
Li, L., Cao, L., Gu, Y., Kim, J., Rejtar, T., Wu, S. And Karger,
B.L., "A New Algorithm for 15N/14N Quantitation with LC-ESI-MS
Using an LTQ-FT Mass Spectrometer", J. of Proteome Res,
5; 2039-2045, (2006).
Moskovets,
E., Preisler, J., Chen, H.S., Rejtar, T., Andreev, V. and Karger.
B.L., "High-Throughput Axial MALDI-TOF MS Using a 2 kHz Repetition
Rate Laser", Anal. Chem., 78, 912-919 (2006).
Karger, Barry L. "Shigeru Terabe, a Colleague and Outstanding
Scientist", J. of Chrom, A., 3, 1106 (2006).
Li, Q., Li, L., Rejtar, T., Lessner, D., Karger, B.L. and Ferry,
J.G., "Electron Transport in the Pathway of Acetate Conversion
to Methane in the Marine Archaeon Methanosarcina acetivorans",
J. of Bacteriol., 188(2), 702-710, (2005).
Chen, H., Rejtar, T., Andreev, V., Moskovets, E. and Karger, B.L.,
"A New Strategy for Enhanced Characterization of Complex Proteomic
Samples Using LC-MALDI MS/MS: Exclusion of Redundant Peptides from
MS/MS Analysis in Replicate Runs" Anal. Chem, 77,
7816 -7825 (2005).
Wu, S., Kim, J., Hancock, W.S., Karger, B.L., "Extended Range
Proteomic Analysis (ERPA): New anad Sensitive LC-MS Platform for
High Seqeucne Coverage of Complex Proteins with Extensive Posttranslational
Modifications -Comprehensive Analysis of Beta-Caesin and Epidermal
Growth Factor Receptor", J. of Proteome Res., 4(4);
1155-1170 (2005).
Li-Sucholeiki, X., Tomita-Mitchell, A., Arnold, K., Glassner, B.,
Thompson, T., Murthy, J., Berk, L., Lange, C., Leong-Morgenthaler,
P., MacDougall, D., Munro, J., Cannon, D., Mistry, T., Miller, A.,
Deka, C., Karger, B.L., Gillespie, K., Ekstrom, P., Todd, J. and
Thilly, W. " Detection and Frequency Estimation of Rare Varients
in Pools of Genomic DNA from Large Populations Using Mutational
Spectrometry", Mutation Research, 570, 267-280
(2005).
Li, Q., Deka, C., Glassner, B., Arnold, K., Li-Sucholeiki, X., Tomita-Mitchell,
A., Thilly, W. and Karger, B.L., "Design of an Automated Instrument
with Fraction Collection for DNA Mutation Discovery by Constant
Denaturant Capillary Electrophoresis (CDCE)." J. of Separation
Science, 28 1375-1389 (2005).
Chen, H., Rejtar, T., Andreev, V., Moskovets, E. and Karger, B.L.
"High Speed - High Resolution Monolithic Capillary LC-MALDI
MS Using an Off-line Continuous Deposition Interface for Proteomic
Analysis", Anal. Chem., 77, 2323-2331 (2005).
Pashkova, A., Chen, H., Rejtar, T., Zang, X., Giese, R. Andreev,
V., Moskovets, E. and Karger, B.L. "Coumarin Tags for Improved
Analysis of Peptides by MALDI-TOF MS and MS/MS. II. Alexa Fluor
350 Tag for Increased Peptide and Protein Identification by LC-MALDI-TOF/TOF
MS", Anal. Chem., 77(7); 2085-2096, (2005).
Li , Q, Li, L, Rejtar, T, Karger, B.L. and Ferry, J. "The Proteome
of Methanosarcina acetivorans. Part II, Comparison of Protein
Abundance in Acetate- and Methanol-Grown Cells", J. of Proteome
Res., 4(1); 129-135 (2005).
Li, Q, Li, L, Rejtar, T, Karger, B.L. and Ferry, J. "The Proteome
of Methanosarcina acetivorans.
Part I, An Expanded View of the Biology of the Cell"
J. of Proteome Res., 4(1), 112-128 (2005).
Kautz, R., Goetzinger, W. and Karger, B.L. "High Throughput
Microcoil NMR of Compound Libraries Using Zero-Dispersion Segmented
Flow Analysis", The Journal of Combinatorial Chemistry,
7(1); 14-20. (2005).
Wu, S., Jardine, I., Hancock, W.I. and Karger, B.L. "A New
and Sensitive On-Line LC-MS Approach for Top-Down Protein Analysis:
The Comprehensive Analysis of Human Growth Hormone in an E. coli
Lysate Using a Hybrid Linear Ion Trap Fourier Transform Ion Cyclotron
Resonance (FTICR) Mass Spectrometer", Rapid Comm. Mass Spec.,
19, 2201-2207 (2004).
Rejtar, T., Chen, H., Andreev, V., Moskovets, E., and Karger, B.L.
"Increased Identification by Peptides by Enhanced Data Processing
of High Resolution MALDI TOF/TOF Mass Spectra Prior to Database
Searching", Anal. Chem., 76, 6017-6028 (2004).
Pashkova, A., Moskovets, E. Karger, Barry L. "Coumarin Tags
for Improved Analysis of Peptides by MALDI-TOF MS and MS/MS I. Enhancement
in MALDI MS Signal Intensities", Anal. Chem., 76,
4550-4557 (2004).
Zang, L.,
Palmer-Toy, D., Hancock, W.S., Sgroi, D. and Karger, B.L. "Proteomic
Analysis of Ductal Carcinoma of the Breast Using Laser Capture Microdissection,
LC-MS and 16O/18O Isotopic Labeling",
J. Proteome Res.,3, 604-612 (2004).
Paba, J.; Ricart, C. A. O., Fontes, W., Santana, J. M., Teixeira,
A. R. L.,. Marchese, J., Williamson, B., Hunt, T., Karger, B. L.,
Sousa, M. V., "Proteomic Analysis of Trypanosoma cruzi
Developmental Stages Using Isotope-Coded Affinity Tag Reagents",
J. Proteome Res., 3, 517-524 (2004).
Lazar, I.M., Horvath,C., Yang, Y., Karger, B.L., "Microfluidic
Device for Capillary Electrochromatography-Mass Spectrometry",
Electrophoresis, 24, 3655-3662 (2003).
Moskovets, E., Chen, H., Pashkova, A., Rejtar, T., Andreev, V.P.,
Karger, B.L., "Closely Spaced External Standard: A Universal
Method of Achieving 5 ppm Mass Accuracy Over the Entire MALDI Plate
in MALDI-TOF MS", Rapid Commun. in Mass Spect., 17,
2177-2187 (2003).
Andreev, V.P., Rejtar, T., Moskovets, E., Ivanov, A., Karger, B.L.,
"A Universal Denoising and Peak Picking Algorithm for LC-MS
Based on Matched Filtration in the Chromatographic Time Domain",
Anal. Chem., 75(22), 6314-6326 (2003).
Ivanov, A., Zang, L., Karger, B.L., "Low Attomole ESI-MS and
MS/MS Analysis of Protein Digests Using 20-µm I.D. Polystyrene-Divinylbenzene
Monolithic Capillary Columns", Anal. Chem., 75(20),
5306-5316 (2003).
Ivanov, A., Horvath, C., Karger, B.L., " High-Efficiency Peptide
Analysis on MonolithicMulti-Mode Capillary Columns: Pressure Assisted
CEC/CE Coupled to UV and ESI-MS", Electrophoresis,
24, 3663-3673 (2003).
Guttman, A., Karger, B.L., "Capillary Electrophoresis and the
Human Genome Project", Genomic/Proteomic Tech., 3,
12-20, April/May (2003).
Karger, B.L. " Some Personal Words on the Career of Stellan
Hjerten", J. Chromatogr A. 1004, 7-8 (2003).
Moskovets, E., Karger, B.L. "Mass calibration of MALDI-TOF
MS Including Rise Time of the Delayed Extraction Pulse", Rapid
Commun. in Mass Spec., 17, 229-237 (2003).
Professor
William Hancock
Updated:11/03/2009
Zeng Z, Hincapie M, Haab BB, Hanash S, Pitteri SJ, Kluck S, Hogan
JM, Kennedy J, Hancock WS. The development of an integrated
platform to identify breast cancer glycoproteome changes in human
serum. J Chromatogr A. 2009 Sep 16. [Epub ahead
of print] (pubmed)
Carlage T, Hincapie M, Zang L, Lyubarskaya Y, Madden H, Mhatre
R, Hancock WS. Proteomic profiling of a high-producing
chinese hamster ovary cell culture. Anal Chem. 2009
Sep 1;81(17):7357-62. (pubmed)
Taylor AD, Hancock WS, Hincapie M, Taniguchi N, Hanash SM.
Towards an integrated proteomic and glycomic approach to
finding cancer biomarkers. Genome Med. Jun 4 2009;1(6):57.
(pubmed)
Bell AW, Hancock WS et al. A HUPO test sample study
revealscommon problems in mass spectrometry-based proteomics.
Nat Methods. 2009 6(6), 423-30. (pubmed)
Akella LM, Rejtar T, Orazine C, Hincapie M, Hancock WS "CLUE-TIPS,
Clustering Methods for Pattern Analysis of LC-MS Data"
J Proteome Res. 2009 Oct;8(10):4732-42. (pubmed)
Lu Q, Zheng X, McIntosh T, Davis H, Nemeth JF, Pendley C, Wu SL,
Hancock WS. Development of Different Analysis Platforms
with LC-MS for Pharmacokinetic Studies of Protein Drugs.
Anal Chem. 2009 Nov 1;81(21):8715-23. (pubmed)
Jiang H, Wu SL, Karger BL, Hancock WS. Mass spectrometric
analysis of innovator, counterfeit, and follow-on recombinant human
growth hormone. Biotechnol Prog. Jan-Feb 2009; 25(1):207-18.
(pubmed)
Zheng X, Wu SL, Hincapie M, Hancock WS. Study of the human
plasma proteome of rheumatoid arthritis. J Chromatogr
A. Apr 17 2009,1216(16):3538-45. (pubmed)
Wu, Shiaw-Lin; Jiang, Haitao ; Lu, Qiaozhen ; Dai, Shujia ; Hancock,
William S. and Karger, Barry L. Mass Spectrometric
Determination of Disulfide Linkages in Recombinant Therapeutic Proteins
Using Online LC-MS with Electron-Transfer Dissociation
Anal. Chem. 2009 81(1):112-22 (link)
Plavina T, Hincapie M, Wakshull E, Subramanyam M, Hancock WS.
Increased plasma concentrations of cytoskeletal and Ca2+-binding
proteins and their peptides in psoriasis patients. Clin
Chem. Nov 2008;54(11):1805-14. (pubmed)
Kullolli M, Hancock WS, Hincapie M. Preparation
of a high-performance multi-lectin affinity chromatography (HP-M-LAC)
adsorbent for the analysis of human plasma glycoproteins.
J Sep Sci. Aug 2008; 31(14):2733-9. (pubmed)
Ochoa CD, Baker H, Hasak S, Matyal R, Salam A, Hales CA, Hancock
W, Quinn DA. Cyclic stretch affects pulmonary endothelial
cell control of pulmonary smooth muscle cell growth. Am
J Respir Cell Mol Biol. Jul 2008;39(1):105-12. (pubmed)
Lu Q, Murugesan N, Macdonald JA, Wu SL, Pachter JS, Hancock WS.
Analysis of mouse brain microvascular endothelium using
immuno-laser capture microdissection coupled to a hybrid linear
ion trap with Fourier transform-mass spectrometry proteomics platform.
Electrophoresis. Jun 2008; 29(12):2689-95. (pubmed)
Orazine CI, Hincapie M, Hancock WS, Hattersley M, Hanke JH.
A proteomic analysis of the plasma glycoproteins of a MCF-7
mouse xenograft: a model system for the detection of tumor markers.
J Proteome Res. Apr 2008; 7(4):1542-54. (pubmed)
Dayarathna MK, Hancock WS, Hincapie M. A two step
fractionation approach for plasma proteomics using immunodepletion
of abundant proteins and multi-lectin affinity chromatography: Application
to the analysis of obesity, diabetes, and hypertension diseases.
J Sep Sci. Apr 2008; 31(6-7):1156-66. (pubmed)
Pandey A, Hancock WS et al. Human Proteinpedia enables
sharing of human protein data. Nat Biotechnol.
Feb 2008;26(2):164-7. (pubmed)
Ralin DW, Dultz SC, Silver JE, Kullolli M, Hancock WS and Hincapie
M. Kinetic Analysis of Glycoprotein-lectin Interactions
by Labal Free Internal Reflection" Clin. Proteomics
2008 4,37-46. (link)
Wu, S.-L., Gu, Y., Hanlon, D., Meyer, J., Linder, J., Hancock, W.S.,
and Karger, B.L., "Proteomic Analysis of High-Grade Dysplastic
Cervical Cells Obtained From ThinPrep® Slides Using Laser Capture
Microdissection and Mass Spectrometry", J Proteome Res.,
6, 4256-68 (2007).
Plavina, T., Wakeshull, E., Hancock, W.S., Hincapie, M., "Combination
of Abundant Protein Depletion and Multi-Lectin Affinity Chromatography
(M-LAC) for Plasma Protein Biomarker Discovery", J. Proteome
Res., 662-671 (2007).
Zheng, X.,
Baker, H., and Hancock, W. S., "Analysis of the Low Molecular
Weight Serum Peptidome Using Ultrafiltration and a Hybrid Ion Trap-Fourier
Transform Mass Spectrometer", J. Chromatogr., 1120,
173-184 (2006).
Plymoth, A,
Yang, Z, Lofdahl, C. G, Ekberg-Jansson, A, Dahlback, M,, Fehniger,
T. E., Marko-Varga, G., Hancock, W. S., "Rapid Proteome Analysis
of Bronchoalveolar Lavage Samples of Lifelong Smokers and Never-Smokers
by Micro-Scale Liquid Chromatography and Mass Spectrometry",
Clin. Chem., 52, 671-679 (2006).
Wang, Y., Wu,
S. L. and Hancock, W. S., "Approaches to the Study of N-linked
Glycoproteins in Human Plasma Using Lectin Affinity Chromatography
and Nano-HPLC Coupled to Electrospray Linear Ion Trap - Fourier
Transform Mass Spectrometry (LTQ/FTMS)", Glycobiology,
16, 514-523 (2006).
Wang, Y., Wu,
S .L. and Hancock, W. S., "Monitoring of Glycoprotein Products
in Cell Culture Lysates Using Lectin Affinity Chromatography and
Capillary-HPLC Coupled to Electrospray Linear Ion Trap - Fourier
Transform Mass Spectrometry (LTQ/FTMS)", Biotechnology Progress,
22, 873-880 (2006).
Zheng, X.,
Wu, S. L., and Hancock, W. S., "Glycation of Interferon-beta-1b
and human serum albumin in a lyophilized glucose formulation",
Int. J. Pharmaceutics, 322, 136-145 (2006).
Yang, Z., Harris,
L. E., Palmer-Toy, D. E. and Hancock, W. S., "Characterization
of Multiple Glycoprotein Biomarker Candidates in Serum from Breast
Cancer Patients Using Multi-lectin Affinity Chromatography (M-LAC)",
Clin. Chem., 52, 1897-1905 (2006).
Wang, Y., Dai,
D., Sadee, W. and Hancock, W.S., "A Pharmacoproteomics Study
of the Cancer Cell Line EKVX", Mol. Pharmaceutics, 5,
566-578 (2006).
Zheng, X.,
Baker, H., Hancock, W. S., Fawaz, F., McCaman, M. and Pungor, E.,
"Proteomic Analysis for the Assessment of Different Lots of
Fetal Bovine Serum as a Raw Material for Cell Culture", Biotechnology
Progress, 5, 1294-1300 (2006).
Hancock, W. S.,
Wang,Y., Yang, Y., and Gruia-Gray, J, "Multidimensional Liquid
Chromatography: A High-Resolution, Reroducible, and Versatile Technique
for Proteomic Analysis of Complex Biological Samples, American
Laboratory, 16-19 (2005).
Wang, ,Y.,Wu, S.-L. Hancock, W.S., Trala, R., Kessler, M., Taylor,
A.H., and Aon, J.C., "Proteomic Profiling of Escherichia coli
Proteins under High Cell Density Fed-batch Cultivation with Overexpression
of Phosphogluconolactonase", Biotech. Progr., 5,
1401 - 1411 (2005).
Ping P, Vondriska T.M., Creighton C.J., Gandhi T, Yang Z, Menon R,
Kwon M.S., Cho S.Y., Drwal G, Kellmann M, Peri S, Suresh S, Gronborg
M, Molina H, Chaerkady R, Rekha B, Shet A.S., Gerszten R.E., Wu H,
Raftery M, Wasinger V, Schulz-Knappe P, Hanash S.M., Paik Y.K., Hancock
W.S., States D.J., Omenn G.S., Pandey A., "A functional annotation
of subproteomes in human plasma", Proteomics. 13 :3506-19
(2005).
Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H,
Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan
DW, Rai AJ, Admon A, Aebersold R, Eng J, Hancock WS, Hefta SA, Meyer
H, Paik YK, Yoo JS, Ping P, Pounds J, Adkins J, Qian X, Wang R, Wasinger
V, Wu CY, Zhao X, Zeng R, Archakov A, Tsugita A, Beer I, Pandey A,
Pisano M, Andrews P, Tammen H, Speicher DW, Hanash SM, "Overview
of the HUPO Plasma Proteome Project: Results from the pilot phase
with 35 collaborating laboratories and multiple analytical groups,
generating a core dataset of 3020 proteins and a publicly-available
database", Proteomics, 5(13) 3226-45 (2005).
Wu, S.-L, Kim, J.K., Hancock, W.S., and Karger, B.L.,"Extended
Range Proteomic Analysis (ERPA): A New and Sensitive LC-MS Platform
for High Sequence Coverage of Complex Proteins with Extensive Posttranslational
Modifications - Comprehensive Analysis of Beta-Casein and Epidermal
Growth Factor Receptor (EGFR)", J.Proteome Res., 4(4)
1155-1170 (2005).
Hancock, W.S., Wang,Y., Yang, Z., and Gruia-Gray,"Multidimensional
Liquid Chromatography: A High-Resolution, Reproducible, and Versatile
Technique for Proteomic Analysis of Complex Biological Samples",
American Laboratory, 16-19 (2005).
Yang, Z., Hancock, W.S., Richmond-Chew, T., Bonilla, L., "A Study
of Glycoproteins in Human Serum and Plasma Reference Standards (HUPO)
using Multi-Lectin Affinity Chromatography Coupled with RPLC-MS/MS",
Proteomics, (13):3353-66.(2005).
Yang, Z.. and Hancock, W.S "Monitoring Glycosylation Pattern
Changes of Glycoproteins Using Multi-lectin Affinity Columns",
J. Chromatogr. A, 1070, 57-64 (2005).
Baker, H., Patel, V., Molinolo, A.A., Shillitoe, E.J., Ensley, J.F.,
Yoo, G.H., Meneses-Garcia, A., Myers, J.N., El-Naggar, A.K., Silvio
Gutkind, J. and Hancock, W.S., "Proteome-Wide Analysis of Head and
Neck Squamous Cell Carcinomas Using Laser-Capture Microdissection
and Tandem Mass-Spectrometry", J. Proteome Res., 41,
183-199 (2005).
Yang, Z-P. and Hancock, W.S. "Approach to the Comprehensive Analysis
of Glycoproteins Isolated from Human Serum Using a Multi-lectin Affinity
Column", J. Chromatogr. A, 1053, 79-88 (2004).
Wang, Y., Hancock, W.S., Weber, G., Eckerskorn, C. and Palmer-Toy,
D., "Free Flow Electrophoresis Coupled with Liquid Chromatography-Mass
Spectrometry for a Proteomic Study of the Human Cell Line (K562/CR3)",
J. Chromatogr. A, 1053, 269-278, (2004).
Wu, S.-L, Jardine, I., Hancock, W.S., and Karger, B.L."A New and Sensitive
On-Line Liquid Chromatography/Mass Spectrometric Approach for Top-Down
Protein Analysis: The Comprehensive Analysis of Human Growth Hormone
in an E.coli Lysate Using a Hybrid Linear Ion Trap/Fourier
Transform Ion Cyclotron Resonance (FTICR) Mass Spectrometer", Rapid
Commun. Mass Spectrom., 19, 2201-2207 (2004).
Zang, L., Palmer-Toy, D., Hancock, W.S., Sgroi, D. and Karger, B,
"Proteomic Analysis of Ductal Carcinoma of the Breast Using Laser
Capture Microdissection, LC-MS and 16O/18O Isotopic Labeling, J.Proteome
Res., 3, 604-612 (2004).
Wu, S.-L., Choudhary, G., Ramström, M., Bergquist, J. and Hancock,
W.S., "An Evaluation of Shotgun Sequencing for Proteomic Analysis
of Human Plasma Using HPLC Coupled with Either Ion Trap Or Fourier
Transform Mass Spectrometry", J. Proteome Res., 2
383-393 (2003).
Stanley, R. and Hancock, W.S., "Bioinformatics in the Clinic:
Challenges and Opportunities for Improved Trials and Clinical Care",
Genomic/Proteomic Technology, 3, 36 (2003).
Wu, S.-L., Shieh, P. Hancock, W.S., Kunitaki, S.T., and Goodrich,
G.G., "A Proteomic Approach to the Detection of Novel Marker
Proteins in a Breast Cancer Cell Line (SKBR-3)", Proteomics,
3, 1037-46 (2003).
Choudhary, G., Wu, S.-L., Shieh, P., and Hancock, W.S., "Multiple
Enzymatic Digestion for Enhanced Sequence Coverage of Proteins in
Complex Proteomic Mixtures using Capillary LC with Ion Trap MS/MS",
J. Proteome Res., 2, 59-67 (2003).
Professor John Engen
See Engen Group
Publications List
Professor Roger Giese
Wang, P., Kremsky,
J. N., Giese, R. W., "Positive chemical ionization (PCI)-like
behavior of estradiol in matrix-assisted laser desorption/ionization",
Rapid Commun. Mass Spectrom., 23, 2836-2838 (2009). (pubmed)
Wang, Y.,
Cui, G., Zhao, M., Yang, J., Wang, C. Giese, R. W., Peng, S., "Bioassay-directed
purification of an acidic phospholipase A(2) from Agkistrodon halys
pallas venom", Toxicon 51, 1131-1139 (2008). (pubmed)
Yong,
L. C., Schulte, P. A., Kao, C-K., Giese, R. W., Boeniger, M. F.,
Strauss, G. H.S., Petersen, M. R., Wiencke, J. K., "DNA Adducts
in Granulocytes of Hospital Workers Exposed to Ethylene Oxide",
Am. J. Ind. Med., 50, 293-302.09 (2007).
Shao, G.,
Kautz, R., Peng, S., Cui, G., Giese, R. W., "Calibration by
NMR for quantitative analysis: p-Toluenesulfonic acid as a reference
substance", J. Chromatogr. A, 1138, 305-308 (2007).
Murugaiah,
V., Naim, A., Peng, S., Cui, G., Giese, R. W., "4-(4'-Methyltetrafluorophenyl)-2,3,5,6-tetrafluorobenzyl
bromide: A new electrophoric derivatizing reagent", J. Chromatogr113.
A, 4, 338-340 (2006).
Shimelis, O.,
Giese, R. W., "Nuclease P1 digestion/high-performance liquid
chromatography, a practical method for DNA quantitation", J.
Chromatogr. A., 1117, 132-136 (2006).
Pashkova, A., Chen, H., Rejtar, T., Zang, X., Giese, R., Andreev,
V., Moskovets, E. Karger, Barry L. "Coumarin Tags for Improved
Analysis of Peptides by MALDI-TOF MS and MS/MS. II. Alexa Fluor
350 Tag for Increased Peptide and Protein Identification by LC-MALDI-TOF/TOF
MS", Anal. Chem., 4(1), 129-135 (2005).
Kao, C-Y., Giese, R.W., Measurement of N7(2-Hydroxyethyl)guanine
in Human DNA by Gas Chromatography Electron Capture Mass Spectrometry,
Chem. Res. Toxicol, 18, 70-75 (2005).
Guttman, A., Giese, R. W. eds. Bioanalytical Chemistry: Perspectives
and Recent Advances, J. Chromatogr. A, 1053 (2004).
Shimeilis, O., Zhou, X., Li, G., Giese, R. W. Phenolic extraction
of DNA from mammalian tissues and conversion to deoxyribonucleoside-5'-monophosphates
devoid of ribonucleotides, J. Chromatogr. A., 1053,
143-149 (2004).
Shao, G., Giese, R. W. Trace Detection of Glycolic Acid by Electrophore
Labeling Gas Chromatography-Electron Capture Mass Spectrometry,
Anal. Chem., 76, 3049-3054 (2004).
Li, G., Shimelis, O., Zhou, X., Giese, R. W. Scaled-Down Nuclease
P1 for Scaled-Up DNA Digestion, BioTechniques 34,
908-909 (2003).
Li, G., Gao, J., Zhou, X., Shimelis, O., Giese, R. W. Handling and
detection of 25 amol of near-infrared dye deoxynucleotide conjugates
by capillary electrophoresis with laser-induced fluorescence detection,
J. Chromatogr. A, 1004, 47-50 (2003).
Giese, Roger W. Measurement of endogenous estrogens: analytical
challenges and recent advances, J. Chromatogr. A, 1000,
401-412 (2003).
Professor Graham Jones
Zhang, N., Lin, Y., Xiao, Z., Jones, G. B., and Goldberg, I. H.,
"Solution Structure of a Designed Spirocyclic Helical Ligand
Binding at a Two-Base Bulge Site in DNA", Biochemistry,
46, 561 (2007).
Jones, G. B., Lin, Y., Xiao, Z., Kappen, L., and Goldberg, I.
H., "Molecular Probes of DNA Bulges: Functional Assay and Spectroscopic
Analysis", Bioorg Med Chem., 15, 784 (2007).
Xiao, Z., Zhang, N., Lin, Y. Jones, G.B., and Goldberg, I. H.,
"Spirocyclic Helical Compounds as Binding Agents for Bulged
RNA, Including HIV-2 TAR", Chem Commun., 4431 (2006).
Swamy, N., Purohit, A., Fernandez-Gacio, A., Jones, G. B., and
Ray, R., "Nuclear Estrogen Recepter Targeted Photodynamic Therapy:
Selective Uptake and Killing of MCF-7 Breast Cancer Cells by a C17a-Alkynylestradiol-Porphyrin
Conjugate", Journal of Cellular Biochemistry, 99,
966 (2006).
Torregrossa, J., Bubley, G. J., and Jones G. B.,"Microwave
Expedited Synthesis of 5-Aminocamptothecin Analogs: Inhimbitors
of Hypoxia Inducible Factor HIF-1a", Bioorganic & Medicinal
Chemistry Letters., 16, 6082-6085 (2006).
Jones, G. B.,
Crasto, C. F., Mathews, J. E., Xie, L., Mitchell, M. O., El-Shafey,
A., D'Amico, A. V., and Bubley, G. J., "An Image contrast agent
selectively activated by prostate specific antigen (PSA)",
Bioorganic and Medicinal Chemistry, 14, 418 (2006).
Shenoy, D., Fu, W., Crasto, C., Sridhar, S., Amiji, M., Li, J.,
Weinberg, J., Jones, G., "Functionalized heterobifunctional
poly[ethylene glycol] templates for use in cellular trafficking
and imaging studies", Int. Journal of Nanomedicine,
1, 51 (2006).
Xie, L. and Jones, G.B., "Exploiting Shielding Interactions:
A Highly Selective Chiral Auxiliary derived from a Biogenic Building
Block", Tetrahedron Lett. 46, 3579 (2005).
Li, J., Crasto, C. F., Weinberg, J., Amiji, M., Shenoy, D., Sridhar,
S., and Jones, G. B., "An Approach to Heterobifunctional Poly(ethyleneglycol)
Bioconjugates", Bioorg. Med. Chem. Lett. , 15,
5558 (2005).
Fouad, F. S., Wright, J. M., Plourde, G., II., Purohit, A. D., Wyatt,
J. K.; El-Shafey, A., Hynd, G., Crasto, C. F., Lin, Y., Jones, G.
B., "Synthesis and Protein Degradation Capacity of Photoactivated
Enediynes", .J. Org. Chem.; 70, 9789 (2005).
Lin, Y., Jones, G. B., Hwang, G.-S., Kappen, L., Goldberg, I. H.,
"Convenient Synthesis of NCS-Chromophore Metabolite Isosteres:
Binding Agents for Bulged DNA Microenvironments", Org. Lett.,
7, 71 (2005).
Oh, W. K., Kantoff, P. W., Weinberg, V., Jones, G., Rini, B. I.,
Derynck, Robert Bok, Matthew R. Smith, Glenn J. Bubley, Robert T.
Rosen, M. K., DiPaola, R. S., Small, E. J., "A Prospective,
Multicenter, Randomized Phase II Trial of the Herbal Supplement,
PC-SPES, and Diethylstilbestrol in Patients with Androgen-Independent
Prostate Cancer", , J. Clin. Oncol., 22, 3705
(2004).
Oh, W. K., Kantoff, P. W., Weinberg, V., Jones, G., Rini, B. I.,
Derynck, Robert Bok, Matthew R. Smith, Glenn J. Bubley, Robert T.
Rosen, M. K., DiPaola, R. S., Small, E. J., "A Prospective,
Multicenter, Randomized Phase II Trial of the Herbal Supplement,
PC-SPES, and Diethylstilbestrol in Patients with Androgen-Independent
Prostate Cancer", , J. Clin. Oncol., 22, 3705
(2004).
Hwang, G.-S., Jones, G. B., and Goldberg, I. H., "Sterochemical
Control of Small Molecule Binding to Bulged DNA: Comparison of Structures
of Spirocyclic Enantiomer-Bulged DNA Complexes", Biochemistry,
43, 641 (2004).
Jones, G. B., and Fouad, F. S., "Designed Enediyne Antitumor
Agents", Frontiers in Medicinal Chemistry, 1,
189 (2004).
Crasto, C. F., and Jones, G. B., "A Practical method for preparation
of ?-glycosides of N-Acetylglucosamine", Tetrahedron Lett
, 45, 4891 (2004). .
Jones, G. B., Xie, L., El-Shafey, A., Crasto, C. F., Bubley, G.
J., and D'Amico, A. V., "Image contrast agents activated by
prostate specific antigen (PSA)", Bioorg. Med. Chem. Lett.,
14, 3081 (2004).
Fouad, F. S., Xie, Z., Goldberg, I. H., and Jones, G. B., "Preparation
of Alkylation Agents for Bulged DNA Microenvironments", Bioorg.
Med. Chem. Lett., 14, 3337 (2004).
Fouad, F. S., Crasto, C. F., Lin, Y., and Jones, G.B.,"Photoactivated
Enediynes: Targeted Chimeras which undergo PhotoBergman Cyclization",
Tetrahedron Lett, 45, 7753 (2004).
Jones, G.B., Russell, K.C., "The Photo Bergman Cycloaromatization
of Enediynes", CRC Handbook of Photochemistry, 29-1
(2003).
Kappen, L.S., Xi, Z., Jones, G.B., Goldberg, I.H., "Stimulation
of DNA Strand Slippage Synthesis by a Bulge Binding Synthetic Agent",
Biochemistry, 42, 2166 (2003).
Hu, Y., Dehal, S. S., Hynd, G., Jones, G. B, .Kupfer, D., "CYP2D6
- catalyzes tamoxifen aromatic hydroxylation with an NIH-Shift",
Xenobiotica, 33, 141 (2003).
Hwang, G-S, Jones, G. B., Goldberg, I. H., "Solution structure
of a wedge-shaped synthetic molecule at a two-base bulge site in
DNA", Biochemistry, 42, 8472 (2003).
Professor Bill Giessen
B. C. Giessen, K. Xu, J. Chen, J. Yao, Z. Zhao, T. Yu, and K. Dadkhah,
"Short Time Segment Price Forecasts Using Spline Fit Interactions
Which Simulate Cycle Analysis", in: "Practical Fruits
of Econophysics, Business Models in the 21st Century - Risk Management
and Expectations for Econophysics", Proc. 3rd Nikkei Econophysics
Symp., H. Takayasu, ed., Springer, Tokyo (2006) p. 111.
B.C. Giessen, Z. Zhao, J. Chen, J. Yao, K. Xu, T. Yu, and K. Dadkhah,
"Successful Price Cycle Forecasts in S&P Futures Using
"TFX", a Family of Pattern Recognition Algorithms Based
on the KNN Method", in: "Practical Fruits of Econophysics,
Business Models in the 21st Century - Risk Management and Expectations
for Econophysics", Proc. 3rd Nikkei Econophysics Symp., H.
Takayasu, ed., Springer, Tokyo (2006) p. 116.
J. Yao, J. Chen, K. Xu, Z. Zhao, T. Yu, B. C. Giessen, and K. Dadkhah,
"Market Cycle Turning Point Forecasts by an Interactively Learning
Algorithm as a Trading Tool for S&P Futures", in: "Practical
Fruits of Econophysics, Business Models in the 21st Century - Risk
Management and Expectations for Econophysics", Proc. 3rd Nikkei
Econophysics Symp., H. Takayasu, ed., Springer, Tokyo (2006) p.
131.
B.C. Giessen and R. Hidalgo, "Alloys", Chapter in "Encyclopedia
of Inorganic Chemistry, 2nd Ed.", Wiley (2005).
S-Q. Wang, B. C. Giessen and R. S. Markiewicz, "Phase equilibrium
in Y-Ba-Cu-O system", Mater. Lett., 57 (2003) 2110-2115.
S-Q. Wang, R. A. Bigelow, R. S. Markiewicz and B. C. Giessen, "Magnetic-alignment
properties of REBa2Cu4O8 (RE=Ho,
Er)", Mater. Lett., 57 (2003) 3449-3454. S-Q. Wang, R. S. Markiewicz
and B. C. Giessen, "Phase equilibrium in Eu-Ba-Cu-O system",
J. Cryst. Growth, 254 (2003) 279-284.
Professor
Paul Vouros
Glick J, Xiong W, Lin Y, Noronha AM, Wilds CJ, Vouros P. The
influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene
diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
J Mass Spectrom. Jun 17 2009; [Epub ahead of print] (pubmed)
Lin Y, Schiavo S, Orjala J, Vouros P, Kautz R. Microscale
LC-MS-NMR platform applied to the identification of active cyanobacterial
metabolites. Anal Chem. 2008 80(21):8045-8054. (link)
Wood JT, Williams JS, Pandarinathan L, Courville A, Keplinger MR,
Janero DR, Vouros P, Makriyannis A, Lammi-Keefe CJ. "Comprehensive
profiling of the human circulating endocannabinoid metabolome: clinical
sampling and sample storage parameters." Clin
Chem Lab Med. 2008 Jul 8. [Epub ahead of print]
pubmed
Schiavo S, Ebbel E, Sharma S, Matson W, Kristal BS, Hersch S, Vouros
P. Metabolite identification using a nanoelectrospray LC-EC-array-MS
integrated system. Anal Chem. Aug 2008; 80(15):5912-23.
pubmed
Liao, Q., Chiu, N. H. L., Shen, C., and Vouros, P., Investigation
of the Enzymatic Behavior of Benzonase /Alkaline Phosphatase in
the Digestion of DNA and DNA Adducts by ESI-LC/MS, Anal.
Chem., 79, 1907-1917 (2007).
Andrews, C.L., Li, F., Yu, C.P., Yang, E., and Vouros, P., Incorporation
of a Nanosplitter Interface into an LC-RD-MS System to Facilitate
Drug Metabolism Studies, Journal of Mass Spectrom.
41, 43-49 (2006).
Levin, D.S.,
Vouros, P., Miller, R.A., Nazarov, E.G., Morris, J.C., Characterization
of gas phase interactions utilizing a novel nanoelectrospray ionization
- differential mobility - mass spectrometer (nanoESI-DMS-MS) system,
Anal. Chem., 78, 96-106 (2006).
Ricicki, E.M.,
Andrews, C.L., Schiavo, S., and Vouros, P., Analysis of DNA
Adducts, in Encyclopedia of Mass Spectrometry, Volume 3, Biological
Applications Part B: Carbohydrates, Nucleic Acids and other Biological
Compounds, Series editors: Caprioli, R. and Gross, M., Elsevier
Ltd., Oxford, 2006, pp. 61-85.
Simionato,A.V.C.
, de Souza, G.D., Rodrigues-Filho,E., Glick, J., Vouros, P., and
Carrilho, E., Tandem mass spectrometry of coprogen and deferoxamine
hydroxamic siderophores, Rapid Commun. Mass Spectrom.,
20, 193-199 (2006).
Levin, D.S.,
Miller, R.A., Nazarov, E.G. and Vouros, P., Rapid separation
and quantitative analysis of peptides using a new nanoelectrospray
differential mobility spectrometer mass spectrometer
system Anal. Chem., 78, 5443-5452 (2006).
Ricicki, E.M.,
Luo, W., Zarbl, H., and Vouros, P., Quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl
Adducts in Human Lymphoblastoid TK6 Cells Dosed with N-hydroxy-4-aminobiphenyl
and their Relationship to Mutation, Toxicity, and Gene Expression
Profiling, Anal. Chem., 78, 6422-6432 (2006).
Williams, J.,
Pandarinathan, L., Wood, J.A., Vouros, P, Makriyannis, A., Endocannabinoid
Metabolomics: A Novel Liquid ChromatographyMass Spectrometry
Reagent for Fatty Acid Analysis", AAPS Journal. 2006;
8(4): E655-E660. DOI: 10.1208/aapsj080474.
Brown, A. J., Ritter,
C.S., Weiskopf, A.S., Vouros, P, Sasso, G. J., Uskokovic. M.R.,
Wang, G, Reddy, G. S. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin
D3, a potent suppressor of parathyroid hormone secretion.,
J. Cell. Biochem. 96(3) :569-78 (2005).
Ricicki, E.M., Andrews, C.L., Schiavo, S., and Vouros, P., Analysis
of DNA Adducts, in Encyclopedia of Mass Spectrometry, Volume
3, Biological Applications Part B: Carbohydrates, Nucleic Acids
and other Biological Compounds, Series editors: Caprioli, R. and
Gross, M., Elsevier Ltd., Oxford, 2005, 61-85.
Rozen, S., Cudcowicz, M.E., Bogdanov, M., Matson, W.R., Kristal,
B. S., Beecher, C., Harrison, S., Vouros, P., Flarakos, J., Vigneau-Callahan,
K., Matson, T.R., Newhall, K.M., Beal, M.F., Brown, R.H. and Kaddurah-Daouk,
R., "Metabolomic analysis and signatures in motor neuron disease",
Metabolomics, 1, 101-108 (2005).
Argoti, D., Liang, L., Conteh, A., Chen, L., Bershas, D., Yu, C-P.,
Vouros, P., Yang, E. Cyanide Trapping of Iminium Ion Reactive
Intermediates Followed by Detection and Structure Identification
Using Liquid Chromatography-Mass Spectrometry (LC/MS), Chem.
Res. Toxicol., 18, 1537-1544 (2005).
Luo, W., Fan, W., Xie, H., Jing, L.; Zhao, L.P., Ricicki, E., Vouros,
P. and Zarbl, H., "Phenotypic Anchoring of Global Gene Expression
Profiles Induced by N-hydroxy-4-acetylaminobiphenyl and Benzo(a)pyrene
Diol Epoxide Reveals Correlations between Expression Profiles and
Mechanism of Toxicity", Chem. Res. Toxicol. 18,
619-629 (2005).
Flarakos, J., Xiong, W., Glick, J., and Vouros, P. "A Novel
Deoxynucleotide Derivatization Methodology for Improving LC-ESI-MS
Detection", Anal. Chem., 77, 2373-2380 (2005).
Ricicki, E.M., Soglia, J.R., Teitel, C., Kane, R., Kadlubar, F.
and Vouros, P., "Detection and Quantification of N-(deoxyguanosine-8-yl)-4-aminobiphenyl
Adducts in Human Pancreas Tissue Using Capillary Liquid Chromatography-Microelectrospray
Mass Spectrometry", Chem. Res. Toxicol. 18, 692-699,
(2005).
Flarakos, J., Morand, K. and Vouros, P., "High Throughput Solution-Based
Medicinal Library Screening against Human Serum Albumin", Anal.
Chem., 77, 1345-1353 (2005).
Astecker, N., Bobrovnikova, E.A., Omdahl, J.L., Gennaro, L.A., Vouros,
P., Schuster, I., S., Ishizuka, Wang, G., Reddy, G.S., “C-25 Hydroxylation
of the Antipsoriatic Drug 1á,24(R)-Dihydroxyvitamin D3 Is Catalyzed
by 25-Hydroxyvitamin D3-24-Hydroxylase (CYP24A1): Metabolism Studies
with Human Keratinocytes and Recombinant CYP24A1”, Archives Biochem.
Biophys., 431, 261-270 (2004).
Andrews, C.L., Yu, C-P., Yang, E., and Vouros, P., “Improved liquid
chromatography–mass spectrometry performance in quantitative analysis
using a nanosplitter interface”, Journal of Chromatography A,
1053, 151-159 (2004).
Andrews, C.L., Harsch, A. and Vouros, P., "Analysis of the in vitro
Digestion of Modified DNA to Oligonucleotides by LC-MS and LC-MS/MS",
Intern. J. Mass Spectrom., 231, (2-3), 169-177 (2004).
Gennaro, L.A., Vadhanam, M., Gupta, R.C. and Vouros, P., "Selective
Digestion and Novel Cleanup Techniques for Detection of Benzo[a]pyrene
Diol Epoxide-DNA Adducts by CE/MS", Rapid Commun. Mass Spectrom.,
18, 1541-1547 (2004).
Flarakos , J., Luo, W., Aman, M., Svinarov, D., Gerber, N., and
Vouros, P., "Quantification of Risperidone and 9-Hydroxyrisperidone
in Plasma and Saliva from Adult and Pediatric Patients by Liquid
Chromatography/ Mass Spectrometry", J. Chromatogr. A, 1026,
175-181 (2004).
Turesky, R.J. and Vouros, P., "Formation and Analysis of Heterocyclic
Aromatic Amine- DNA Adducts in vitro and in vivo",
J. Chromatogr. B, 802 (1) 155-166 (2004).
Marzilli, L.A., Fay, L. B., Dionisi, F. and Vouros, P., "Structural
Characterization of Triacylglycerols Using Electrospray Ionization-MSn
Ion Trap MS", J. Assoc. Off. Anal. Chem., 80,
195-202 (2003)
Gennaro, L.A., Harvey, D.J. and Vouros, P., "Reversed- phase
ion-pairing liquid chromatography/ion trap mass spectrometry for
the analysis of negatively charged, derivatized glycans", Rapid
Commun. Mass Spectrom., 17, 1528-1534 (2003).
Professor
Zhaohui Sunny Zhou
Dorgan, K.M.,
Wooderchak, W.L, Wynn, D.P., Karschner, E.L., Alfaro, J.F., Cui,
Y., Zhou, Z.S., Hevel, J.M., "An enzyme-coupled continuous
spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases",
Anal Biochem., Mar 15;350(2):249-55 (2006).
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