Facilities and Instrumentation
The laboratories of the 8 Institute Faculty Fellows house a complementary array of state-of-the-art instrumentation for bioanalytical and elemental microanalysis, building on the Institute's traditional strength in separation science.
I. Mass Spectrometry:
The Institute operates over 20 mass spectrometers, interfaced to a variety of specialized instrumentation.
• Thermo-Fisher LTQ-FT (Hybrid Linear Ion Trap + Fourier Transform MS).
• Thermo-Fisher LTQ-ETD ( Linear Ion Trap with Electron Transfer Dissociation)
• Waters "Synapt" IMS-MS
• Waters Q-TOF Premier XE (electrospray quadrupole/time- of- flight)
• Waters Q-TOF API US (Electrospray quadrupole Time-of-Flight, W-optics)
• "Proteomics Workstation" AB 4700 MALDI TOF-TOF MS
• Micromass QTOF1 QP TOF MS
• Waters LCT Premier XE (Electrospray Time-of-Flight, W-optics)
• Waters LCT Classic(LCT Classic)
• 2 Agilent 5973 GC-MS
• Applied Biosystems Mariner ESI orthogonal extraction TOF-MS
• Applied Biosystems Voyager DESTR TOF-MS
• 2 Thermo-Fisher LTQ Linear Ion Trap
• Thermo-Fisher LCQ Deca XP 3D ion trap MS
• 3 Thermo-Fisher LCQ Classic 3D ion trap MS
• Thermo-Fisher TSQ 700 triple QP MS
• Thermo-Fisher TSQ 7000 triple QP MS
• SCIEX API III PLUS triple QP MS
• A 32-node computer cluster for bioinformatic analysis and software development
• Automation Systems
II. Separation Instrumentation
This list includes free-standing LC systems as well as units integrated into mass spectrometers or NMR instrumentation.
• Beckman Proteome Lab 2D LC System
• Custom Waters Nano-Acquity UPLC
• Eksigent nanoLC System
• 3 Dionex Ultimate nanoLC systems
• Advion Nanomate 100
• Bio-Rad 2D gel electrophoresis system
• 6 Agilent 1100 HPLC systems
• 2 Agilent 1100 Cap HPLC systems
• 4 Agilent 1090 HPLC's
• 1 Agilent G 1602 CE system
• 1 Amersham Biosciences MDLC system
• 2 Amersham Biosciences AKTA FPLC system
• 5 Beckman CE systems
• 1 Varian HPLC system
• 1 Bischoff HPLC system
• 2 Thermo Electron Surveyor LC systems
• 3 Shimadzu HPLC systems
III. NMR and LC-NMR
The James and Faith Waters 500 MHz NMR Facility
500 MHz NMR System (Varian Unity-Inova)
• Microcoil NMR
• High-throughput microcoil sample loading
(2 uL samples from 96-well plates, using segmented flow)
• Conventional 5 mm NMR
• LC NMR
• High-Throughput Flow NMR
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